LIVELUNG - Impact of CGA in Patients Diagnosed With Localized NSCLC Treated With SBRT

Odense University Hospital

Status

Enrolling

Conditions

Non-small Cell Lung Cancer

Comprehensive Geriatric Assessment

Stereotactic Body Radiotherapy

Treatments

Other: Comprehensive Geriatric Assessment

Study type

Observational

Funder types

Other

Identifiers

NCT05919641

LIVELUNG

Details and patient eligibility

About

Older patients with non-small cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT) often die from other causes than lung cancer due to age-related comorbidities. This national randomized study will include 130 patients throughout 5 Danish cancer centres and investigate if a comprehensive geriatric intervention (CGA) when added upfront to SBRT for patients with localized NSCLC will have an impact on quality of life (QoL), overall survival, physical functionality and unplanned hospital admissions.

If an upfront CGA improves patients' general health status, this study could lead to implementation of a CGA in standard clinical practice as well as further research on older patients receiving radiotherapy.

Enrollment

130 estimated patients

Sex

All

Ages

70+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with cytologically or histologically proven non-small cell lung cancer
Stage T1-3N0M0
≥ 70 years old
In a multidisciplinary setting the patient is considered medically inoperable, too frail for operation due to age and/or comorbidity or that the patient refuse surgery and therefore candidate for SBRT.

Exclusion criteria