Liver Disease in Adults With Alpha-1 AT Deficiency (LIDIA-A1AT)

Civil Hospices of Lyon

Status: Completed

Conditions: Alpha-1 AT Deficiency

Treatments: Other: Transient Elastography and fibrotest

Study type: Interventional

Funder types: Other

Identifiers

NCT01455298

2011.664

Details and patient eligibility

About

This cohort study will evaluate the prevalence of the infra clinical liver injuries among a group of adult patients presenting with Alpha-1 AT deficiency followed up in a large university hospital in Lyon, France.

Enrollment: 33 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients over 18 years old
• Presenting an Alpha-1 AT deficiency (Alpha-1 AT level <0.8g/l at the time of diagnosis)

Exclusion criteria

• Patients presenting a liver disease not related to the Alpha-1 AT deficiency

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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33 participants in 1 patient group

Transient elastography and fibrotest

Other group

Treatment:

Other: Transient Elastography and fibrotest