Liver Embolization Approaches for Tumor Management (LEATUM)

San Donato Group (GSD)

Status: Enrolling

Conditions: Primary Liver Cancer; Metastatic Cancer; Metastatic Pancreatic Cancer; Hepatocellular Carcinoma; Cholangiocarcinoma; Metastatic Gastric Cancer; Metastatic Colon Cancer

Treatments: Procedure: Embolization

Study type: Observational

Funder types: Other

Identifiers

NCT05714124

LEATUM

Details and patient eligibility

About

The goal of this evaluate short, medium and long term outcome of the different embolization techniques in patients with primary and secondary hepatic tumors. The main aim is to evaluate progression free survival following embolization in this study population or evaluate residual hepatic volume in cases in which these techniques are used to induce liver regeneration. This study is an observational registry - all patients will follow their normal therapeutic and treatment scheme as per clinical practice, without any additional intervention.

Enrollment: 580 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ≥ 18 yoa
• patients with patients with primary or secondary liver disease not amenable for surgery or ablation
• patients with primary or secondary liver tumors candidates for major surgery prior to induction of hypertrophy
• able and willing to sign informed consent

Exclusion criteria

• pregnant women
• patients with uncorrectable coagulopathy
• diffuse extrahepatic disease
• for lobar TACE and TARE - presence of bilodigestive shunt
• for TARE - >20% hepatopulmonary shunt