Liver Fat Quantification by Magnetic Resonance Imaging (MRI) - Prediction of Postoperative Complications (MRsteatosis)

University of Zurich (UZH)

Status: Completed

Conditions: Fatty Liver; Surgery

Treatments: Procedure: Major liver resection; Other: Non-invasive Magnetic Resonance Imaging (MRI)

Study type: Observational

Funder types: Other

Identifiers

NCT01234714

MRI_Steatosis_Outcomes

Details and patient eligibility

About

The purpose of this study is to objectively quantify liver fat content (LFC) by Magnetic Resonant Imaging (MRI) prior to major liver surgery, and to investigate its association with post-operative complications.

Full description

Lack of agreement exists among expert pathologists in the standard histological assessment of hepatic steatosis on biopsy. The impact of different grades of steatosis on postoperative complications after major liver resection remains controversial.

Enrollment: 84 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Major liver resection (>= 3 resected segments).
• Patients that received a pre-operative Magnetic Resonance Imaging (MRI).
• Patient over 18 years of age

Exclusion criteria

• Patients that underwent liver surgery but < 3 segments were resected (e.g. wedge liver resection).
• Patient that did not receive a pre-operative MRI
• Patient age less than 18 years of age.

Trial design

84 participants in 1 patient group

Major liver resection

Description:

This single Cohort/Group will include all consecutive patients that received pre-operative Magnetic Resonant Imaging (MRI) and underwent major liver resection (\>=3 segments).

Treatment:

Other: Non-invasive Magnetic Resonance Imaging (MRI)

Procedure: Major liver resection