Liver Ischemia-reperfusion Injury and Clinical Data Analysis

Qin Zhang

Status: Enrolling

Conditions: Liver Injury

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06080308

TJ-IRB20230940

Details and patient eligibility

About

Searching for new targets for the diagnosis and treatment of liver ischemia-reperfusion injury.

Full description

Through the analysis of serological data during liver resection elective surgery with hepatic pedicle occlusion and reperfusion, as well as the analysis of patient-related data, we aim to identify key target points that affect reperfusion injury and explore their underlying mechanisms.

Enrollment: 270 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Willingness to participate in the study and has signed an informed consent form. 2) Age ≥ 18 years and ≤ 70 years. 3) ASA classification ≤ III. 4) Criteria for liver ischemia-reperfusion injury patients: patients undergoing elective liver resection surgery with hepatic pedicle occlusion and reperfusion during the procedure.

Exclusion criteria

1. Patients with adverse events during surgery. 2) Patients in the end stage of disease with liver failure. 3) Liver tumor metastasis with concomitant severe heart failure or chronic renal insufficiency, etc. 4) Deemed unsuitable for participation in the study based on the judgment of the researchers.