Local Anesthesia and Tuberculin Skin Test in Infants and Children

Assistance Publique - Hôpitaux de Paris

Status

Unknown

Conditions

Tuberculosis

Treatments

Drug: lidocaine / Prilocaine

Study type

Interventional

Funder types

Other

Identifiers

NCT00309673

CRC05001

Details and patient eligibility

About

The use of local anaesthesia efficiently reduces pain due to needle puncture. However, when tuberculin skin test is performed it is the skin reaction to tuberculin injection that is studied. It is a quantitative skin reaction measured in millimiters. From the study of literature it is not known whether local anaesthetic modify skin reaction to tuberculin. Therefore, before recommending the use local anaesthesia for tuberculin intradermal injection we have to rule out a potential effect of local anaesthetic on the result of the test. This is particularly important in children, since there are more sensitive to pain than adults

Sex

All

Ages

1 month to 15 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

hospitalized or non hospitalized infant or child (3 months-15 years)requiring a tuberculin skin test, in our hospital. hospitalized 1 to 3 months old infants requiring a tuberculin skin test, in our hospital.

Exclusion criteria

child with contra indication to the use of Lidocaine / prilocaine
child with evolutive dermatitis on forearms
premature or newborn (less than 1 month of age)
infants (1 - 24 months of age)who has yet received repeated local anaesthesia (at least 2)during the 24 previous hours
infants (1 - 24 months of age)who is treated with a drug that could enhance the risk of methhaemoglobinemia
child with previous evere local reaction to tuberculin injection (necrosis,ulceration)
child with history of tuberculosis disease
child with hepatic failure
parents or the child himself if lod enough, have not given their agreement for the study