Local Anesthetic Infiltration and Infusion for Pain Control After Hip Replacement

Trinity Health Of New England

Status: Completed

Conditions: Osteoarthritis

Treatments: Procedure: Normal Saline; Procedure: Ropivacaine infiltration and saline infusion.; Procedure: Ropivacaine infiltration and infusion.

Study type: Interventional

Funder types: Other

Identifiers

NCT01409278

09-07-002

Details and patient eligibility

About

The purpose of this study is to examine three different ways to control pain after hip replacement:

1. One time injection of ropivacaine before wound closure
2. One time injection of ropivacaine before wound closure plus slow release of ropivacaine via catheter for 48 hours
3. Standard practice of patient controlled pump

Enrollment: 105 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• total knee replacement

Exclusion criteria

• History of neurological disease, diabetes, pregnancy, allergy to local anesthetic solutions chronic narcotic use ability to consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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105 participants in 3 patient groups, including a placebo group

Ropivacaine infiltration and infusion.

Experimental group

Description:

Ropivicaine infiltration followed by continuous ropivicaine infusion for 48 hours.

Treatment:

Procedure: Ropivacaine infiltration and infusion.

Ropivacaine and Saline

Experimental group

Description:

Ropivicaine infiltration followed by normal saline infusion.

Treatment:

Procedure: Ropivacaine infiltration and saline infusion.

Saline infiltration and infusion.

Placebo Comparator group

Description:

Normal saline infiltration followed by saline infusion.

Treatment:

Procedure: Normal Saline