Local Assessment of Ventilatory Management During General Anesthesia for Surgery (LAS VEGAS)

European Society of Anaesthesiology

Status: Completed

Conditions: Pneumothorax; Lung Injury; Anaesthesia; Respiratory Insufficiency; Surgery; Respiratory Distress Syndrome, Adult; Ventilator-Induced Lung Injury; Pneumonia

Study type: Observational

Funder types: Other

Identifiers

NCT01601223

LAS VEGAS

Details and patient eligibility

About

Objectives

1. To characterize mechanical ventilation practices during general anesthesia for surgery
2. To assess the dependence of intra-operative and post-operative pulmonary complications on intra-operative Mechanical Ventilation (MV) settings

Full description

Research questions

• What MV-settings are used during general anesthesia for surgery?
• Do MV-settings vary in and/or between centers?
• Do MV-settings vary internationally?
• Are MV-settings associated with incidence of intra-operative pulmonary complications?
• Are MV-settings associated with incidence of post-operative pulmonary complications?

Enrollment: 10,690 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• All surgical procedures requiring invasive mechanical ventilation (MV)during general anesthesia for laparoscopic or non-laparoscopic surgery.
• This includes MV performed with supra-glottic devices (e.g. laryngeal mask)
• This includes patients receiving MV at the onset of the procedure (e.g. Intensive Care Unit patients)
• This includes patients who will receive one-lung ventilation during the procedure

Exclusion criteria

• Obstetric surgical procedures or any procedure during pregnancy
• Surgical procedures outside the operating room
• Surgical procedures involving extra-corporal circulation

Trial design

10,690 participants in 1 patient group

Surgical mechanically-ventilated

Description:

Surgical patients undergoing invasive mechanical ventilation for general anesthesia