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Local GIT Hormones After Bariatric Maneuvers

M

Minia University

Status

Unknown

Conditions

Morbid Obesity

Treatments

Procedure: sleeve gastrectomy with loop bipartition

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Background: Many of the beneficial metabolic effects of bariatric surgery have been attributed to altered peptide hormone profiles, especially involving pancreatic and gut peptides.

Objectives: assess the effects of bariatric procedures (sleeve gastrectomy, minigastric bypass and sleeve gastrectomy with loop bipartition) on GIT hormones. Methods: Prospective randomized study which was carried out in the department of General Surgery, Minia University hospital during the period from February 2018 to February 2019. This study included 3 groups subjected to different operations; each group consisted of 50 patients.

Full description

Prospective randomized study which was carried out in the department of General Surgery, Minia University hospital during the period from February 2018 to February 2019. This study included 3 groups subjected to different operations; each group consisted of 50 patients. Age ranging from 20 to 50 years old and body weight ranging from 100 to 200 Kg, and subjected to laparoscopic sleeve gastrectomy, mini gastric bypass and sleeve gastrectomy with loop bipartition. Each patient was thoroughly evaluated by a multidisciplinary team (Nutritionist, Endocrinologist, Psychologist, and Surgeon) using a standardized protocol. Follow up was done after two weeks and after 2 months.

Enrollment

150 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

All morbid obese patients

Exclusion criteria

GIT diseases

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

150 participants in 3 patient groups

laparoscopic sleeve gastrectomy
Active Comparator group
Treatment:
Procedure: sleeve gastrectomy with loop bipartition
mini gastric bypass
Active Comparator group
Treatment:
Procedure: sleeve gastrectomy with loop bipartition
sleeve gastrectomy with loop bipartition
Active Comparator group
Treatment:
Procedure: sleeve gastrectomy with loop bipartition

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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