Local Injection of PRP During Repair of Disrupted Surgical Wounds

Tanta University

Status: Completed

Conditions: Role of Platelet Rich Plasma in Wound Healing

Treatments: Procedure: Closure of wound without platelet rich plasma infiltration; Procedure: Platelet rich plasma infiltration in the wound edges

Study type: Interventional

Funder types: Other

Identifiers

NCT03781882

PRP surgical wounds

Details and patient eligibility

About

Patients with disrupted wounds will either managed as usual or managed by Platelet rich plasma local infiltration in the wound edges

Full description

The patients with disrupted surgical wounds will be cleansed, debrided and closed with infiltration of platelet rich plasma in one group and the other group will be closed without infiltration of Platelet rich plasma

Enrollment: 220 patients

Sex: Female

Ages: 20 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Disrupted surgical wounds after cesarean sections and other gynecological operations
• Body mass index 18-25
• Hemoglobin > 10.5gm/dl
• Albumin >3.5gm/dl

Exclusion criteria

• Medical disorders asDiabetes mellitus (DM), Liver disease or systemic lupus erythymatosus (SLE)
• Patient on corticosteriod therapy
• Thrombocytopenia
• Coagulation disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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220 participants in 2 patient groups

Intervention group

Active Comparator group

Description:

All patients in this group will be manged as usual with infiltration of platelet rich plasma in thee wound edges during closure of the wounds

Treatment:

Procedure: Platelet rich plasma infiltration in the wound edges

Control group

Active Comparator group

Description:

All patients in this group will be managed by repair of wounds without infiltration of platelet rich plasma

Treatment:

Procedure: Closure of wound without platelet rich plasma infiltration