Local Triamcinolone Injection in Active Thyroid Orbitopathy

HaEmek Medical Center, Israel

Status: Unknown

Conditions: Thyroid Disease

Treatments: Drug: Triamcinolone

Study type: Interventional

Funder types: Other

Identifiers

NCT01280214

EMC119710ctil

Details and patient eligibility

About

Comparing the effectiveness of subconjunctival and peribulbar Triamcinolone injection to systemic Steroid therapy for patients with active thyroid orbitopathy.

Full description

Local Steroid treatment may help in active thyroid orbitopathy. till today, systemic Steroids are the treatment for active thyroid orbitopathy which is associated with systemic adverse effects.

In this study the investigators want to compare the effectiveness of local Triamcinolone therapy for active thyroid orbitopathy.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age>18 years.
• Active thyroid orbitopathy according to clinical activity score>=3.

Exclusion criteria

• Intraorbital or active infections.
• Tuberculosis.
• Other orbital disease.
• Pregnancy.
• Compressive optic neuropathy.
• Systemic steroid therapy within 6 months of study start.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Triamcinolone

Experimental group

Treatment:

Drug: Triamcinolone