Local Vibration in Multiple Sclerosis Patients

Hacettepe University

Status: Unknown

Conditions: Multiple Sclerosis

Treatments: Other: Standard physiotherapy program; Other: Standard physiotherapy program+50 Hz local vibration; Other: Standard physiotherapy program+100 Hz local vibration

Study type: Interventional

Funder types: Other

Identifiers

NCT04192786

KA-19018

Details and patient eligibility

About

Gastrocnemius spasticity is one of the main complaints in Multiple Sclerosis patients.Local muscle vibration is a method used for spasticity inhibition. However, when the studies in the literature are examined; It is noted that local vibration applications for spasticity are usually single sessions and evaluate the acute effect, do not produce functional outputs, there is no consensus on frequency and amplitude and the changes in muscle architecture are not examined. In this study, we aimed to investigate the effect of local vibration applied on spastic gastrocnemius on muscle architectural and functional properties in Multiple Sclerosis patients in addition to the standard physiotherapy program. The study was planned to include 3 groups, 2 treatment and 1 control group. The control group will receive standard physiotherapy, one of the treatment groups will receive 50 Hz local vibration in addition to standard physiotherapy, and other treatment group will receive 100 Hz local vibration in addition to standard physiotherapy. Disease severity, gastrocnemius spasticity, architectural and viscoelastic properties of muscle, ankle proprioception, balance and gait skills will be evaluated before and after 8 weeks treatment program. As a result; effectiveness of local vibration in addition to standard physiotherapy program and whether there is a difference between applications at different frequencies will be examined.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• > 18 years
• EDSS<5,5
• Gastrocnemius spasticity<2

Exclusion criteria

• having any injury or surgery of the lower extremity
• having systemic and metabolic disease
• having behavioral and cognitive problems that prevent consistence to guidelines given

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 3 patient groups

Treatment Group 50 Hz

Experimental group

Treatment:

Other: Standard physiotherapy program+50 Hz local vibration

Treatment Group 100 Hz

Experimental group

Treatment:

Other: Standard physiotherapy program+100 Hz local vibration

Control Group

Active Comparator group

Treatment:

Other: Standard physiotherapy program