Localization of Intercostal Perforating Vessels Reduces Wound Complications From Nipple Sparing Mastectomy

Amita Health

Status

Unknown

Conditions

Breast Cancer

Treatments

Procedure: Ultrasound for localizing intercostal perforating vessels

Study type

Observational

Funder types

Other

Identifiers

NCT02938390

Nipple Sparing Study

Details and patient eligibility

About

Approximately 100 women scheduled for NSM will be consented pre-operatively to participate in the study. US will be performed after induction of general anesthesia, prior to surgery using Sonosite™ portable US, 5-12mHz transducer using doppler mode.

Full description

Nipple Sparing Mastectomy (NSM) has been increasingly utilized over the last ten years for risk-reducing surgery and surgical treatment for breast cancer. The oncologic safety has been well established in multiple studies in appropriately selected individuals. Additionally, rates of wound complications and risk factors for wound problems are well documented. The intercostal perforating vessels (IPV) have been demonstrated to provide a significant proportion of the blood supply to the nipple-areolar complex1-3. Thus, preservation of these vessels is essential to reducing ischemic necrosis of the nipple-areolar complex. We propose that localization of these vessels utilizing intra-operative ultrasound (US) will reduce ischemic necrosis complications of NSM.

Objectives

Demonstrate that US is an effective means of localizing the IPV intraoperatively.
Evaluate the frequency of IPV preservation with the use of US.
Measure rate and severity of ischemic necrosis when US is utilized to preserve IPV.
Compare observed rate with historical controls.

Enrollment

100 patients

Sex

Female

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria