Localizing the Epileptogenic Zone With High Resolution Electroencephalography (EEG-HR)

Central Hospital, Nancy, France

Status: Completed

Conditions: Partial Epilepsy

Treatments: Device: Stereo-electroencephalography; Device: High Resolution EEG

Study type: Interventional

Funder types: Other

Identifiers

NCT01090934

2009-A00574-53

Details and patient eligibility

About

Multicenter prospective study comparing the diagnosis value of high-resolution EEG and depth-EEG to localize the epileptogenic zone in drug resistant partial epilepsies.

Enrollment: 115 patients

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• medically intractable patial epilepsy confirmed by video-EEG recordings of epileptic seizures.
• Depth EEG (Stereo-EEG) required to delineate the epileptogenic zone and define the surgical procedure.
• full informed consent of the patient (or of his/ her legal representative)
• 15 year or older patient

Exclusion criteria

• contraindication to cortectomy

• contraindication to depth-EEG

• indication of epilepsy surgery without depth-EEG monitoring

• high grade glioma, arterio-veinous malformations

  • pregnancy
  • history of severe cardio-vascular event (coronaropathy, stroke)

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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115 participants in 2 patient groups

high resolution EEG

Experimental group

Treatment:

Device: High Resolution EEG

Stereo Electroencephalography

Active Comparator group

Treatment:

Device: Stereo-electroencephalography