Loneliness and Occurrence of Suicide Attempts and Suicidal Ideas (SOLSTIS)

University Hospital Center (CHU)

Status: Completed

Conditions: Major Depressive Disorders

Treatments: Other: Clinical and biological assessment

Study type: Interventional

Funder types: Other

Identifiers

NCT02829671

2016- -A00276-45 (Other Identifier)

UF 9702

Details and patient eligibility

About

Suicide is a major health problem that causes annually a million death worldwide. Loneliness is known to be associated with suicidal ideation in minors and to be related with suicidal risk in elderly people. However little is known about this association in a middle-aged population. Loneliness is a modifiable factor with suitable psychotherapeutic measures, it is essential to improve the scientific and medical knowledge about the link between this feeling and suicide risk in a population of depressed patients in middle age.

The main objective is the study of the relationship between loneliness and the occurrence of suicidal behavior (SB) in major depressed adult population over 12 months.

The secondary objectives are:

• Identification of risk factors (clinical, neuropsychological and biological) of the occurrence of SB within a clinical population and their interaction;
• Identification of predictive factors (clinical, neuropsychological, biological) therapeutic response to antidepressant in the context of depression.

Full description

This project is based on clinical, neuropsychological and biological data routinely collected in the Department of Emergency Psychiatry and Post Acute Care. This is a one year follow-up prospective study.

Over three years, 600 depressed patients will be recruited.

• First visit (inclusion): clinical, biological and neuropsychological assessment
• Follow up visits (3, 6 and 12 months): clinical assessment only

Enrollment: 600 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Main diagnosis of major depressive disorder according to Diagnostic and Statistical Manual of Mental DisordersIV (DSM IV) Having signed informed consent Able to understand nature, aims, and methodology oh the study

Exclusion criteria

Participation in another clinical trial Patient on protective measures (guardianship or trusteeship)

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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600 participants in 1 patient group

Patients with major depressive disorders

Other group

Treatment:

Other: Clinical and biological assessment