Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery

Jewish General Hospital

Status and phase: Completed; Phase 3

Conditions: Coronary Artery Bypass Graft Surgery

Treatments: Drug: Standard of care; Drug: Parasternal blocks

Study type: Interventional

Funder types: Other

Identifiers

NCT05191745

2022-3125

Details and patient eligibility

About

This is a randomized, double-blind, controlled clinical trial is to evaluate the duration of efficacy of parasternal blocks with the use of local anesthetic adjuncts for analgesia after coronary artery bypass grafting surgery.

Full description

This study will randomize patients to either standard pain control protocols or parasternal blocks after coronary artery bypass grafting-only surgery. This study will specifically examine the effectiveness and duration of analgesia of parasternal blocks with local anesthetic adjuncts, Dexamethasone 10mg and Dexmedetomidine 50mcg, added to the local anesthetic mixture

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients coming for elective and urgent coronary artery bypass (CABG)-only surgery.

Exclusion criteria

• Patients with a history of regular opioid use.
• Patients with a history of chronic pain.
• Patients unable to provide consent.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Intervention group

Experimental group

Description:

Patients will receive bilateral parasternal blocks at the end of cardiac surgery.

Treatment:

Drug: Parasternal blocks

Control group

Placebo Comparator group

Description:

Patients will receive all standard care as per the hospital protocols.

Treatment:

Drug: Standard of care