Long-term Assessment of Organ Functions Among Survivors of Severe Acute Respiratory Syndrome

P

Peking University

Status

Unknown

Conditions

Long-Term Survivors
SARS Virus

Study type

Observational

Funder types

Other

Identifiers

NCT03443102
2018PHB010-01

Details and patient eligibility

About

SARS-CoV has caused severe epidemic respiratory disease in human populations. By July 2003, a total of 8,096 probable cases of SARS had been reported including 774 deaths in 27 countries, around one-third of which were health care workers (HCWs). Previous studies have been reported about long-term impacts of SARS infection, including lung function deficiency, steroid-induced osteonecrosis, reduced exercise capacity, and impairment in health-related quality of life (HRQoL). HCWs, especially nurses, have been reported to experience greater psychological distress, particularly increased levels of posttraumatic stress symptomatology (PTSS). But the very complex impacts of this fatal infection on HCWs have not been fully elucidated. It is thus important to follow these occupational patients to detect and manage multi-organ sequelae and functional impairment.

Enrollment

150 estimated patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Health care workers who were working at Peking University People's Hospital during the SARS epidemic in 2002-2003

Exclusion criteria

Refusal to continue the study

Trial design

150 participants in 2 patient groups

SARS survivors
Description:
First-line HCWs infected during the SRAS-CoV pandemic in Peking University People's Hospital, China. Diagnose was further confirmed by SARS-CoV seropositive results.
Controls
Description:
Coworkers of the infected HCWs, who also exposed to SARS patients or specimens. Infection was further excluded by SARS-CoV seronegative results. Healthy controls matched for age, sex and disease condition, but without exposures to SARS virus.

Trial contacts and locations

1

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Central trial contact

Jia Li, Dr; Yali Zheng, Dr

Data sourced from clinicaltrials.gov

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