Long-Term Behavioral and Cognitive Outcomes of Deep Brain Stimulation in Patients With Parkinson's Disease

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Enrolling

Conditions: Parkinson Disease

Treatments: Diagnostic Test: Clinical examinations and clinical scales administration

Study type: Observational

Funder types: Other

Identifiers

NCT06329726

NeuroPsico_DBS&PD

Details and patient eligibility

About

The goal of this observational study is to evaluate the long-term effect of DBS-STN on cognitive and behavioral outcomes in Parkinson's disease (PD) patients.

PD patients will be assessed over time using tests, questionnaires and standardized clinical scales. An initial assessment (T0) and annual follow-up assessments will be carried out for 5 years.

Researchers will compare data collected from patients with DBS versus patients with best medical therapy.

Enrollment: 52 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parkinson's disease patients candidates for DBS of the subthalamic nucleus
• Parkinson's disease patients with best medical treatment

Exclusion criteria

• patients unable to complete study assessments

Trial design

52 participants in 2 patient groups

PD - undergone DBS

Description:

Patients with Parkinson's disease treated with DBS of the subthalamic nucleus

Treatment:

Diagnostic Test: Clinical examinations and clinical scales administration

PD - not undergone DBS

Description:

Patients with Parkinson's disease not treated with DBS

Treatment:

Diagnostic Test: Clinical examinations and clinical scales administration