Long-term Cohort Study of Mesorectal Excision for Rectal Cancer (TME-KSW)

Kantonsspital Winterthur KSW

Status: Enrolling

Conditions: Cancer; Rectum

Treatments: Procedure: Total mesorectal excision for rectal cancer

Study type: Observational

Funder types: Other

Identifiers

NCT05112016

TME-KSW

Details and patient eligibility

About

The aim of this cohort study is to record, evaluate and compare the surgical, oncological as well as the functional outcome and Quality of life after mesorectal excision for rectal cancer

Full description

Outcomes of mesorectal excision patients will be analysed. Medical records will be reviewed and perioperative outcomes retrieved, incl. long-term oncological and functional/quality of life data. A retrospective cohort over 10 years (2007-2016) will serve as a control to a prospective cohort over 10 further years (2017-2026) as to investigate trends in perioperative and oncological outcomes (min. follow-up of 5 years + adequate cohort size). Prospective data on bowel function, urogenital function and quality of life will measured at time of diagnosis and further. Variations in neoadjuvant/adjuvant treatment and surgical approaches will be assessed for their effect on the outcomes of interest.

Enrollment: 250 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Men and Women >18 years
• Patients with rectal cancer
• Underwent mesorectal excision
• Agreed to fill in a validated questionnaires before surgery and after stoma reversal
• Informed consent

Exclusion criteria

• Age < 18
• No informed consent (no general consent, no consent to use personal data for research purpose)

Trial design

250 participants in 1 patient group

TME for rectal cancer

Description:

Patients with rectal cancer treated by TME (laparoscopic TME, transanal TME, robotic TME, open TME)

Treatment:

Procedure: Total mesorectal excision for rectal cancer