Long-term Consequences of Neuroimaging and Perceived Cognitive Dysfunction in oPRES

Dunjin Chen

Status: Unknown

Conditions: Neuroimaging; Posterior Reversible Encephalopathy Syndrome; Cognitive Dysfunction

Treatments: Biological: neuroimaging examination,neuro-cognitive test,blood pressure,blood sample

Study type: Observational

Funder types: Other

Identifiers

NCT05140850

82001568

Details and patient eligibility

About

The purpose of this study is to explore the long-term consequences of neuroimaging and perceived cognitive dysfunction in obstetrics posterior reversible encephalopathy syndrome.

Full description

This is a prospective study. The investigators divided the PE or E patients into two groups, namely PRES group and non-PRES group, according to diagnostic criteria . The general information（demographic data，blood pressure.etc.）and blood sample will be collected. Additionally,all patients receive neuroimaging examination（DTI,ASL,3D-TMI.etc.）and neuro-cognitive test（MMSE,MOCA,CFQ, etc.） to assess the cerebral white matter lesions and cognitive changes.

Enrollment: 500 estimated patients

Sex: Female

Ages: 15 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. patients were diagnosed of PE or E
2. patients received cranial image examination
3. patients consent to participate

Exclusion criteria

1. patients combined other neurological diseases
2. patients combined mental illness

Trial design

500 participants in 2 patient groups

PRES group

Description:

PE or E with PRES

Treatment:

Biological: neuroimaging examination,neuro-cognitive test,blood pressure,blood sample

non-PRES group

Description:

PE or E without PRES

Treatment:

Biological: neuroimaging examination,neuro-cognitive test,blood pressure,blood sample