Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology (FERT-ISSUES)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Live Birth Rate; Oncology; Fertility Counseling; Female Cancer Survivors; Patient Follow-up; Reproductive Health; Reproductive Outcomes; Psychological Impact; Cancer Remission; Assisted Reproductive Technology; Fertility Observatory; Fertility Preservation; Fertility Preservation Techniques

Study type: Observational

Funder types: Other

Identifiers

NCT07312058

PI2025_843_0156

Details and patient eligibility

About

Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity.

Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment.

However, few studies have analyzed the long-term reproductive outcomes of these interventions, nor how patients ultimately use or do not use the FP options once in remission.

This project aims to better understand the effectiveness, utilization, and psychological impacts of these strategies.

This work is part of an effort to understand and evaluate fertility preservation practices implemented for women of reproductive age undergoing cancer treatment at the Amiens-Picardie University Hospital (CHU).

Its objective is to document patient pathways, clinical decisions, techniques employed, and reproductive outcomes observed after remission, in order to identify potential areas for improvement in the support and follow-up of these patients, thereby enhancing the overall quality and coordination of care.

This work is conducted alongside the development of a fertility observatory at the Department of Medicine and Reproductive Biology, CHU Amiens-Picardie.

Enrollment: 102 estimated patients

Sex: All

Ages: 18 to 47 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women
• Aged between 18 and 47 years
• Diagnosed with cancer or hematological disorders requiring potentially gonadotoxic treatment
• Having undergone a medical fertility preservation consultation
• Followed at Amiens Picardie University Hospital (CHU Amiens Picardie) in the department of Reproductive Medicine
• Currently in remission
• Having expressed non-opposition to participation in the study

Exclusion criteria

• Absence of remission
• Patients deprived of liberty by administrative or judicial decision, or placed under legal protection (guardianship or curators)
• Decline to participate in the study