Long-term Follow-up Findings of Inpatients for COVID-19 Pneumonia

Koc University Hospital

Status: Completed

Conditions: Covid19

Treatments: Diagnostic Test: spirometry, thoracic CT, CPET, 6 minute walking test, SF-36 questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT04599998

2020.188.IRB1.056

Details and patient eligibility

About

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus (SARS-CoV-2) that can progress to severe multiorgan disease requiring hospitalization. The medium and long-term impact in survivors of COVID-19 on lung function, imaging by thoracic CT, exercise capacity, and health-related quality of life and the relation of these parameters remains to be determined.

Full description

Aim: To evaluate medium to late (visit 1: 6-12 months after hospital discharge) effects of COVID-19 on lung function, exercise capacity, thoracic CT findings, symptoms and HRQoL in patients with confirmed diagnosis of SARS-CoV-2 infection and the relation between these parameters.

Material and methods: Prospective cohort of subjects with laboratory and/or thoracic CT confirmed COVID-19 who were treated as inpatients. Participants will perform spirometry, lung diffusion capacity of carbon monoxide, 6-minute walk test (6MWT) and cardiopulmonary exercise testing (CPET) after 6-12 months (Visit 1) of COVID-19. Clinical, laboratory and chest image data during the COVID-19 hospitalization will be obtained from medical records.

The minimum sample size was estimated as 37 participants.

Enrollment: 28 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients with Covid 19 diagnosis
• Ability to read and speak
• Signed informed consent.
• Able to perform exercise testing and walking

Exclusion criteria

• Subjects with limited exercise capacity

Trial design

28 participants in 1 patient group

COVID-19 inpatients

Description:

Patients with laboratory and/or thoracic CT confirmed COVID-19 pneumonia ; older than18 years of age; treated as inpatients; evaluated at 6-12 months after hospital discharge in outpatient clinic

Treatment:

Diagnostic Test: spirometry, thoracic CT, CPET, 6 minute walking test, SF-36 questionnaire