Long-term Hemodialysis Catheter Removal and Delayed Replacement, Versus Exchange Over a Guidewire to Treat Catheter Related Blood Stream Infection

Ain Shams University

Status: Completed

Conditions: Catheter Related Blood Stream Infection

Treatments: Device: catheter replacement

Study type: Interventional

Funder types: Other

Identifiers

NCT03054714

tunneled hemodialysis

Details and patient eligibility

About

Prospective, randomized Study of tunneled cuffed hemodialysis catheter removal and delayed replacement, versus exchange over a guidewire to treat catheter related blood stream infection

Full description

The aim of this study was to compare the clinical outcomes of catheter-related (CRBSI) managed with two different strategies: Guidewire exchange of the infected catheter with a new one over a guidewire versus catheter removal with delayed replacement.

Enrollment: 798 patients

Sex: All

Ages: 14 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients end stage renal disease on hemodialysis from tunneled cuffed dialysis catheters with suspected catheter-related bloodstream infection with no identifiable infection source except the catheter were included.

Exclusion criteria

• metastatic infection,

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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798 participants in 2 patient groups

group A

Active Comparator group

Description:

exchange of the infected catheter with a new one over a guidewire

Treatment:

Device: catheter replacement

group B

Active Comparator group

Description:

removal of the infected catheter followed by delayed placement of a new catheter 3 to 10 days later

Treatment:

Device: catheter replacement