Long-Term IOP Fluctuation and VF Progression After Triple Procedure

Yonsei University

Status: Completed

Conditions: Glaucoma; Filtering Surgery; Intraocular Pressure

Study type: Observational

Funder types: Other

Identifiers

NCT00428740

3-2006-0388

Details and patient eligibility

About

Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.

Full description

Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in glaucoma patients. However, even if the IOP can been substantially lowered, reduction of mean and peak IOP does not always prevent visual field progression.We believe that the long-term IOP fluctuation may play a significant role in visual field deterioration in those patients.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Underwent triple procedure
2. At leas 3 years of follow-up after surgery
3. IOP <18mmHg at each postoperative visit
4. A minimum of 5 visual field examinations
5. A reference visual field defect score of 16 or less
6. Good reliability indices of visual field

Exclusion criteria

1. Any other significant ocular diseases or intraocular surgical histories,
2. Diseases that may affect visual field or diabetes