Long-term of 10 Years Results of a Prospective Longitudinal Study

Nagaoka Red Cross Hospital

Status: Unknown

Conditions: Type 2 Diabetes Mellitus; Blood Pressure

Treatments: Procedure: Blood pressure measurement based on HBP or CBP

Study type: Observational

Funder types: Other

Identifiers

NCT01557972

5

Details and patient eligibility

About

Previous cross-sectional studies have demonstrated that blood pressure (BP) measurements at home (HBP) in the morning offer stronger predictive power for micro- and macrovascular complications in patients with type 1 and 2 diabetes than casual/clinic blood pressure measurements (CBP) (Kamoi K et al, 2002-2003). Further, a prospective, longitudinal study for 6 years in patients with type 2 diabetes also demonstrated that control of wakening-up HBP provides the stronger predictive power for the outcomes than that of CBP did (Kamoi et al, 2010).

However, it is not clear to show which of BP measurement provides the stronger predictive power for outcomes by comparing cumulative events over a longer time than 6 years. Therefore, the investigators examined which of HBP or CBP provides the stronger predictive power for outcomes in addition of renal anemia reported previously over 10 years in the patients with type 2 diabetes.

Enrollment: 400 estimated patients

Sex: All

Ages: 20 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• After a detailed baseline examination, 400 Japanese subjects with type 2 diabetes reported previously are followed up for all-cause mortality and morbidity.

Exclusion criteria

• Other than the above, patients judged inappropriate as the subjects of this study by the investigator

Trial design

400 participants in 2 patient groups

1. Morning HP and NT

Description:

Subjects based on HBP were divided into MH and MN patients

Treatment:

Procedure: Blood pressure measurement based on HBP or CBP

Procedure: Blood pressure measurement based on HBP or CBP

2. Clinic HP and NT

Description:

Subjects based on CBP were divided into CH and CN patients

Treatment:

Procedure: Blood pressure measurement based on HBP or CBP

Procedure: Blood pressure measurement based on HBP or CBP