Long-term Outcome After Edoxaban Versus Vitamin K Antagonists for Acute VTE (HOKUSAIpostVTE)

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Status: Unknown

Conditions: Quality of Life; Post Thrombotic Syndrome; Chronic Thromboembolic Pulmonary Hypertension; Venous Thromboembolic Disease

Treatments: Other: Observation

Study type: Observational

Funder types: Other

Identifiers

NCT04007653

HOKUSAI post VTE study

Details and patient eligibility

About

The HOKUSAI post VTE study contains of two different research questions; one on the long term outcomes of deep vein thrombosis and one on the long term effects of pulmonary embolism, post thrombotic syndrome (PTS) and chronic thromboembolic pulmonary hypertension (CTEPH) respectively. Our aim of the study is to compare the long term outcomes along with the quality of life assessment of VTE in a group treated with heparin+VKA versus a group treated with heparin+edoxaban in the acute setting.

Enrollment: 1,200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participant in the HOKUSAI VTE trial

Exclusion criteria

• None

Trial design

1,200 participants in 2 patient groups

Patients treated with heparin+edoxaban for VTE

Description:

Patients treated with heparin+edoxaban for a venous thromboembolic event during the HOKUSAI trial, for which they were randomised.

Treatment:

Other: Observation

Patients treated with heparin+VKA for VTE

Description:

Patients treated with heparin+VKA for a venous thromboembolic event during the HOKUSAI trial, for which they were randomised.

Treatment:

Other: Observation