Long-term Outcome of AIDS-related Primary Central Nervous System Lymphoma Treated With High Dose Methotrexate and Combined Antiretroviral Therapy (LCPVIH)

Fondation Ophtalmologique Adolphe de Rothschild

Status: Completed

Conditions: AIDS Related Lymphoma; Central Nervous System Lymphoma

Treatments: Other: Retrospective survival analysis

Study type: Observational

Funder types: NETWORK

Identifiers

NCT03690895

NI_2015_2_AMR

Details and patient eligibility

About

This study aims at describing survival rates over time (Kaplan-Meier estimator) in patients suffering from AIDS-related primary central nervous system lymphoma who were diagnosed from 1996 to 2014 and treated with infusions of high-dose methotrexate and combined antiretroviral therapy.

Enrollment: 51 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV infection
• AIDS-related primary central nervous system lymphoma
• treated with at least one infusion of methotrexate and combine antiretroviral therapy

Exclusion criteria

• prior non-Hodgkin lymphoma

Trial design

51 participants in 1 patient group

Cases

Treatment:

Other: Retrospective survival analysis