Long Term Outcomes of Coronavirus Disease-19 (COVID-19)

Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital

Status: Completed

Conditions: Covid19

Treatments: Diagnostic Test: Chest Computed Tomography; Other: Quality of Life; Diagnostic Test: Pulmonary Function Tests; Other: Six Minutes Walk Test

Study type: Observational

Funder types: Other

Identifiers

NCT04715919

195/ADF14

Details and patient eligibility

About

The investigators hypothese that lung involvement due to COVID-19 may cause structural changes in the lung in the long term. In this study the effects of structural changes in the lung on pulmonary function tests, exercise capacity and quality of life will be examined.

Full description

Coronavirus disease-19 (COVID-19) has a clinical spectrum ranging from asymptomatic cases to severe cases requiring intensive care hospitalization due to respiratory failure. The disease mostly infects the lower respiratory tract. Typical computed tomography findings of lung involvement are bilateral, peripherally located ground glass density and consolidations. There is a close relationship between tomography findings and clinical severity. It is not known whether there will be complete recovery in the lungs.

Investigators will evaluate pulmonary structures with chest computed tomography, respiratory capacity with pulmonary function tests (PFTs), exercise capacity with six minutes walk test and quality of life with short form-36 (SF-36) im patients who survivors of COVID-19 at least 6 months after hospital discharge.

Enrollment: 70 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who were ≥18 years
• COVID-19 confirmed by Real-Time PCR
• At least 6 months after discharge

Exclusion criteria

• Patients who were < 18 years
• Pregnancy
• Become bedridden after discharge

Trial design

70 participants in 2 patient groups

Patients in ICU

Description:

ICU patients with COVID-19

Treatment:

Diagnostic Test: Pulmonary Function Tests

Diagnostic Test: Chest Computed Tomography

Other: Quality of Life

Other: Six Minutes Walk Test

Patients in Hospital Ward

Description:

Patients with COVID-19 in hospital wards

Treatment:

Diagnostic Test: Pulmonary Function Tests

Diagnostic Test: Chest Computed Tomography

Other: Quality of Life

Other: Six Minutes Walk Test