Long Term Outcomes of Patients With COVID-19 (COVID19 LTFU)

The University of Chicago

Status: Active, not recruiting

Conditions: Respiratory Failure; Corona Virus Infection; Critical Illness; Covid-19

Treatments: Other: Impact Event Score; Other: Hospital anxiety and depression scale; Other: Quality of Life

Study type: Observational

Funder types: Other

Identifiers

NCT04360538

20-0538

Details and patient eligibility

About

The investigators hypothesize that those with respiratory failure due to COVID-19 will have different burdens of mental and physical disability than those with respiratory failure who do not have COVID-19. Detecting these potential differences will lay an important foundation for treating long term sequelae of respiratory failure in these two cohorts.

Full description

The aim of this proposal to is to understand the extent and degree of physical disability, psychological sequelae, and cognitive dysfunction survivors of COVID-19 related critical illness will have upon hospital discharge, 6 months, and up to one year post discharge. These outcomes of interest will be evaluated prospectively. The investigators will perform these measures in Covid-19 patients with respiratory failure and compare them to non-Covid-19 patients with respiratory failure. The investigators also seek to determine the risk factors of these long-term complications in order to guide providers as to which patients should be screened for these deficits. Finally, the investigators will examine the association of various critical care interventions such as invasive versus noninvasive mechanical ventilation or use of sedatives and their effects on disability and cognitive dysfunction.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients admitted to the ICU

Exclusion criteria

• none

Trial design

500 participants in 2 patient groups

COVID19 positive

Description:

ICU patients coronavirus positive

Treatment:

Other: Quality of Life

Other: Hospital anxiety and depression scale

Other: Impact Event Score

non-COVID19

Description:

ICU patients without coronavirus

Treatment:

Other: Quality of Life