Long-term Outcomes of Patients With Primary Amyloidosis After Stem Cell Transplantation

Mayo Clinic

Status: Completed

Conditions: Amyloidosis

Study type: Observational

Funder types: Other

Identifiers

NCT01606280

11-005003

Details and patient eligibility

About

This study examines the value of stem cell transplantation in managing light chain amyloidisis.

Full description

1. How does age at diagnosis affect prognosis in primary amyloidosis?

2. How do lab values at diagnosis such as Creatinine, AST/ALT, total serum protein, serum gamma globulin/immunoglobulin levels affect prognosis in primary amyloidosis?

3. How does degree of organ involvement/number of organs involved affect prognosis in primary amyloidosis?

4. How does initial treatment affect prognosis in primary amyloidosis?

5. How do the specifics the stem cell transplant protocol affect prognosis in primary amyloidosis?

Enrollment: 400 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Eligible for Stem cell transplantation less than age 75

Exclusion criteria

• Creatinine > 3.0
• BNP > 10000