Long-term Paired Associative Stimulation as a Treatment for Incomplete Spinal Cord Injury of Non-traumatic Origin

Helsinki University Central Hospital (HUCH)

Status: Completed

Conditions: Spinal Cord Injuries; Spinal Cord Diseases

Treatments: Device: long-term paired associative stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT03104803

ULD 8100014-2

Details and patient eligibility

About

The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles (1). In this study, the investigators will administer long-term paired associative stimulation to patients with incomplete SCI of non-traumatic origin.

Enrollment: 5 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• incomplete SCI of non-traumatic origin

Exclusion criteria

• epilepsy
• metal inclusion in the head area
• pacemaker
• hearing device
• high intracranial pressure

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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5 participants in 2 patient groups

Long-term PAS

Experimental group

Description:

The intervention is given to one hand only

Treatment:

Device: long-term paired associative stimulation

No intervention

No Intervention group

Description:

Contralateral hand of the same patient