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Long-term Physical Training in Chronic Obstructive Pulmonary Disease

U

Universidade Estadual de Londrina

Status

Unknown

Conditions

Pulmonary Disease, Chronic Obstructive

Treatments

Other: Physical training

Study type

Interventional

Funder types

Other

Identifiers

NCT01537627
LFIP-001-NAH-1

Details and patient eligibility

About

Several impairing factors contribute to physical limitation in chronic obstructive pulmonary disease (COPD) as deconditioning, muscle dysfunction and physical inactivity. The available literature clearly indicates that these therapeutic targets benefit from exercise training in patients with COPD and, currently, the key point is not whether patients should or not exercise, but which is the specific contribution of each exercise modality to this population. About this topic, the characteristics of a physical training program to be offered to patients have been a point discussed among researchers in this field, although recently the high-intensity training has been recognized as superior in comparison to the low-intensity training. Literature also indicates that, in order to change the sedentary lifestyle of patients with COPD, long-term training programs are indicated. However, a doubt still remains: if long-term programs are one of the key points to reduce physical inactivity, it is not yet clear whether it is necessary to include high-intensity exercises in that long-term program. If the duration is the only factor influencing the outcomes of the program, thus the intensity of training could be reduced, increasing the adherence of patients to the protocol. Based on this hypothesis, the aim of this study is to compare the effects of two physical training protocols in a long-term rehabilitation program (6 months) in patients with COPD: a high-intensity protocol (based on endurance and resistive training) and a low-intensity protocol (based on callisthenic and breathing exercises training). It is expected that the results of this study contribute to the scientific literature by demonstrating whether low- and high-intensity training contribute equally to change the sedentary lifestyle of patients after a long-term exercise program.

Enrollment

82 estimated patients

Sex

All

Ages

40+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Chronic obstructive pulmonary disease (COPD) diagnosis according to Global Initiative for Chronic Obstructive Lung Disease(GOLD)criteria
  • Clinical stability (i.e. absence of acute exacerbation in the last 3 months)
  • Absence of any unstable/severe cardiac,osteoarticular or neuromuscular disorders which could limit physical activities in daily life
  • Non participation in pulmonary rehabilitation in the last year

Exclusion criteria

  • Being unable to attend the outpatient clinic three times per week
  • Inability to understand or cooperate with the assessment methods

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

82 participants in 2 patient groups

Low-intensity training (LT)
Active Comparator group
Treatment:
Other: Physical training
Other: Physical training
High-intensity training (HT)
Active Comparator group
Treatment:
Other: Physical training
Other: Physical training

Trial contacts and locations

1

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Central trial contact

Fabio Pitta, PhD

Data sourced from clinicaltrials.gov

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