Long Term Results in Redo Mitral Valve Surgery After Mitral Valve Repair

Michele De Bonis

Status: Completed

Conditions: Degenerative Mitral Valve Disease

Treatments: Procedure: Mitral valve replacement; Procedure: Mitral valve repair (PLM)

Study type: Observational

Funder types: Other

Identifiers

NCT05839782

LORESAR

Details and patient eligibility

About

The current gold standard for severe mitral regurgitation is mitral valve plasty (PLM). The surgery allows the repair of the mitral valve, therefore without the need for mitral valve replacement (SVM), which involves the implantation of a biological prosthesis or a mechanical prosthesis.

However, PLM has a rate of failure, between 1-4% per year in degenerative mitral pathologies. As a result, patients with PLM failure and severe residual regurgitation are increasingly presenting in recent years.

Generally these patients are re-operated to replace the mitral valve. Our aim is to investigate the differences in re-operation involving mitral valve replacement or re-repair in patients who underwent mitral valve re-operation (re-repair or replacement) in our center between 2003 and 2017.

Enrollment: 108 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients
• failure of previous mitral valve repair which needed a new surgical treatment
• group Re-PLM: patients reoperated with a new mitral valve repair
• group Re-SVM: patients reoperated with a mitral valve replacement

Exclusion criteria

• urgent/emergent procedures

Trial design

108 participants in 2 patient groups

Re-PLM

Description:

Patient in which a new mitral valve repair is performed to treat failed mitral valve repair

Treatment:

Procedure: Mitral valve repair (PLM)

Re-SVM

Description:

Patient in which a mitral valve replacement is performed to treat failed mitral valve repair

Treatment:

Procedure: Mitral valve replacement