Long Term Results of Amniotic Membrane Transplant in Bullous Keratopathy Patients

Prince of Wales Hospital

Status

Completed

Conditions

Bullous Keratopathy

Treatments

Procedure: Amniotic membrane transplant

Study type

Observational

Funder types

Other

Identifiers

NCT03450954

CRE-2013.687

Details and patient eligibility

About

A retrospective study including 22 patients who have undergone amniotic membrane transplant in our unit up till 2016. Confocal microscopy and anterior segment optical coherence tomography (ASOCT) were performed to assess the retention of amniotic membrane and to detect any corneal structural changes. Comparison was made with 5 controls who had bullous keratopathy awaiting endothelial keratoplasty.

Full description

This retrospective cohort study (CREC Ref No.: CRE-2013.687) was approved by the Joint Chinese University of Hong Kong-New Territories East Cluster Clinical Research Ethics Committee. All patients who had AMT done due to symptomatic bullous keratopathy at the Prince of Wales Hospital and Alice Ho Miu Ling Nethersole Hospital (from 1998 onwards till June 2016) were invited back for confocal microscopy and anterior segment optical coherence tomography (ASOCT) at the clinic by the principal investigator (GS) from October to November 2016.

Enrollment

27 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

All patients who have undergone amniotic membrane transplant in our cluster up till 2016.
Patients who have bullous keratopathy on conservative treatment such as lubricants, bandage contact lens

Exclusion criteria