Long Term Results of Combined Transpupillary Thermotherapy (TTT) Indocyanine Green (ICG) Based Photodynamic Therapy (PDT) in Choroidal Melanoma

New England Retina Associates

Status: Completed

Conditions: Choroidal Melanoma

Treatments: Procedure: TTT + ICG-based PDT

Study type: Observational

Funder types: Other

Identifiers

NCT01253759

NERA-2

Details and patient eligibility

About

This is a report of 10 years results of combined Transpupillary thermotherapy (TTT) treatment with Indocyanine green (ICG) in controlling small and medium-sized choroidal melanomas.

Full description

The study was done in a Clinical practice setting. Forty six eyes of 46 patients with small or medium-sized choroidal melanomas were treated with i-TTT using infrared light delivered from a diode laser. All patients were evaluated to rule out systemic metastasis and underwent a complete ophthalmological evaluation including: Slit lamp biomicroscopy, dilated fundus examination, Fluorescein angiography, Optical coherence tomography and A/B ultrasonography. Main outcome measures were: Changes in visual acuity, complications associated with the treatment and local control of the tumor.

Enrollment: 46 patients

Sex: All

Ages: 18 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Small and medium-sized choroidal melanoma
• Patients older than 18 years old.
• Patients who can read and signed the informed consent.

Exclusion criteria

• Patients with ocular inflammation.
• Patients with another active ocular disease.

Trial design

46 participants in 1 patient group

1

Description:

Combined treatment of Transpupillary Thermotherapy and ICG-based photodynamic therapy (PDT)

Treatment:

Procedure: TTT + ICG-based PDT