Long-term Results of Rehabilitation of Patients With Myocardial Infarction After Coronary Artery Stenting. The Register.

National Medical Research Center for Therapy and Preventive Medicine

Status: Active, not recruiting

Conditions: Myocardial Infarction

Treatments: Other: Physical training program

Study type: Interventional

Funder types: Other

Identifiers

NCT07465692

LCRAS07-01/13

Details and patient eligibility

About

Endovascular intervention is one of the most effective treatment for acute coronary syndrome. Therefore, studying the impact of various medical rehabilitation programs on the course of coronary heart disease, patient quality of life, restenosis, and prognosis is of scientific and practical interest. Medical rehabilitation is a crucial stage in patient care after myocardial revascularization. Regular moderate-intensity physical activity helps improve endothelial function and has anti-inflammatory and antithrombogenic effects. Improving a patient's prognosis after myocardial infarction depends on the duration and intensity of cardiac rehabilitation programs, as well as the patient's motivation. Therefore, this issue requires further study, particularly in patients who have undergone endovascular interventions on coronary arteries.

Full description

The study was an interventional (clinical) trial, randomized in parallel groups. A total of 1,046 patients were included.

A total of 1,046 patients of both sexes were randomized into two groups. Group 1 (control) patients received standard therapy required for patients undergoing coronary artery stenting during the acute phase of myocardial infarction. They continued their usual physical activity and attended a school for patients with myocardial infarction. Group 2 patients received standard therapy required for patients undergoing coronary artery stenting during the acute phase of myocardial infarction, attended a school for patients with myocardial infarction, and participated in a physical training program. The training program lasted over four months. Postoperatively, patients underwent blood tests, echocardiography, ECG, and bicycle ergometry. The next visit was performed after an average of eight years (with a maximum follow-up period of 11 years). Cardiovascular events were assessed at this stage. Patients who were unable to attend the clinic were interviewed by telephone.

Enrollment: 1,046 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute myocardial infarction, coronary artery stenting

Exclusion criteria

• Age (younger 18 years, older 75 years)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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1,046 participants in 2 patient groups

Physical training

Experimental group

Description:

Integrated Rehabilitation consisting of exercise training and school for patients

Treatment:

Other: Physical training program

Control

No Intervention group

Description:

Standard follow-up and attending school for patients at the participating heart center