Long Term Results of the Use of Oxybutynin for the Treatment of Hyperhidrosis

Hospital Israelita Albert Einstein

Status: Completed

Conditions: Hyperhidrosis

Treatments: Drug: Oxybutynin

Study type: Observational

Funder types: Other

Identifiers

NCT01956591

HIsraelitaAE

Details and patient eligibility

About

Evaluate the long term efficacy and side effects of oxybutynin in the treatment of hyperhidrosis.

Full description

This retrospective study aims to evaluate the medical charts of patients who were treated with oxybutynin for at least six months for primary hyperhidrosis. The investigators variables of interest are: (1) quality of life before pharmacological therapy and after six weeks, (2)self-perception of improvement in hyperhidrosis after six weeks of treatment and on last visit (whenever this occur, as long as this happens after six months), (3) side effects related to drug use.

Enrollment: 1,100 patients

Sex: All

Ages: 5+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary hyperhidrosis
• At least 180 days of treatment with oxybutynin

Exclusion criteria

• Incomplete medical chart
• Patients with glaucoma

Trial design

1,100 participants in 5 patient groups

Axillary hyperhidrosis

Description:

Patients whose major complaint is excessive sweating in the axillary region (i.e, sweating in the armpit). Patients that also have hyperhidrosis - but that are less bothersome on other sites (e.g., palmar hyperhidrosis) are not excluded, but are accounted for accordingly to their main complaint.

Treatment:

Drug: Oxybutynin

Palmar hyperhidrosis

Description:

Patients whose major complaint is excessive sweating in the palmar region (i.e, sweating in the hands). Patients that also have hyperhidrosis - but that are less bothersome on other sites (e.g., axillary hyperhidrosis) are not excluded, but are accounted for accordingly to their main complaint.

Treatment:

Drug: Oxybutynin

Plantar hyperhidrosis

Description:

Patients whose major complaint is excessive sweating in the plantar region (i.e, sweating in the feet). Patients that also have hyperhidrosis - but that are less bothersome on other sites (e.g., axillary hyperhidrosis) are not excluded, but are accounted for accordingly to their main complaint.

Treatment:

Drug: Oxybutynin

Cranio-facial hyperhidrosis

Description:

Patients whose major complaint is excessive sweating in the cranio-facial region (i.e, sweating in the face). Patients that also have hyperhidrosis - but that are less bothersome on other sites (e.g., axillary hyperhidrosis) are not excluded, but are accounted for accordingly to their main complaint.

Treatment:

Drug: Oxybutynin

Other sites hyperhidrosis

Description:

Patients whose major complaint is excessive sweating in other sites of the body (e.g., on the chest, on the abdomen). Patients that also have hyperhidrosis - but that are less bothersome on other sites previously grouped (e.g., axillary hyperhidrosis) are not excluded, but are accounted for accordingly to their main complaint.

Treatment:

Drug: Oxybutynin