Longitudinal Evaluation of Active-Duty Personnel with Accessory Pathways (LEAD-AP)

Naval Medical Center

Status: Active, not recruiting

Conditions: Cardiac Death, Sudden; Cardiac Death; Wolf Parkinson White Syndrome

Treatments: Procedure: Standard of care without ablation; Procedure: Ablation

Study type: Observational

Funder types: Other U.S. Federal agency

Identifiers

NCT06798961

NMCSD.2024.0019

Details and patient eligibility

About

The investigators propose a secondary chart review using EMR data to identify risk factors for sudden cardiac death in active-duty members diagnosed with an accessory pathway between the ages of 18-40.

Full description

The LEAD-AP study is a dual arm retrospective observational cohort study (using existing records) to investigate the long-term outcomes of patients diagnosed with an accessory pathway during their military service.

Overall objective: Identifying additional risk factors associated with sudden cardiac death to help with risk stratification and guide ablation criteria for patients diagnosed with accessory pathways between the ages of 18-40.

Specific Aim/Research Question: The investigators will evaluate whether patients with an ablation have improved outcomes.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Active Duty between ages 18-40 who were diagnosed with an accessory pathway between 1/1/1990 - 5/30/2024.

Exclusion criteria

• Patient without the diagnosis of Wolf Parkinson's White (WPW) syndrome

Trial design

1,000 participants in 1 patient group

All patients

Description:

Patients diagnosed with Accessory pathway between ages 18-40.

Treatment:

Procedure: Ablation

Procedure: Standard of care without ablation