Longitudinal Multimodal Neuroimaging Studies in Patients With First Episode Psychosis

Mass General Brigham

Status: Completed

Conditions: Psychotic Disorders

Treatments: Other: Observational

Study type: Observational

Funder types: Other

Identifiers

NCT01688765

2012P001796

Details and patient eligibility

About

The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.

Full description

The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.

The study design is case-control, there are no interventions.

Enrollment: 187 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of first episode of a psychotic disorder
• Healthy controls with no psychiatric disorder history

Exclusion criteria

• Significant neurological or medical illness history
• Ages <18 or >45

Trial design

187 participants in 2 patient groups

First Episode Psychosis Patients

Description:

Individuals experiencing a first episode of psychosis

Treatment:

Other: Observational

Healthy Controls

Description:

Psychiatrically healthy individuals

Treatment:

Other: Observational