Longitudinal Pathogen-colonization in Cystic Fibrosis Airways and Ability to Smell

University of Jena

Status: Unknown

Conditions: Sinusitis; Cystic Fibrosis With Other Manifestations

Treatments: Other: nasal lavage and sputum collection

Study type: Observational

Funder types: Other

Identifiers

NCT00803881

CF_Sinusitis_LS

Details and patient eligibility

About

Aim of the study is to detect the prevalence of chronic rhinosinusitis, pathogen colonization of the lower and upper airways and, in a sub-cohort the sense of smelling in patients with cystic fibrosis.

Full description

The sub-study on the sense of smelling in CF has been finalized in the meantime. Results were published in 2012:

Smell in cystic fibrosis. Lindig J, Steger C, Beiersdorf N, Michl R, Beck JF, Hummel T, Mainz JG. Eur Arch Otorhinolaryngol. 2013 Mar;270(3):915-21. doi: 10.1007/s00405-012-2124-2. Epub 2012 Aug 14.

Enrollment: 180 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Subject has a confirmed diagnosis of cystic fibrosis

Trial design

180 participants in 1 patient group

CF patients of all age groups

Description:

Longitudinal prospective assessment of upper and lower airway colonization in all patients attended in the Jena University CF centre

Treatment:

Other: nasal lavage and sputum collection