Longitudinal Study of Traumatic Brain Injury (TBI) in (University of Florida) UF Athletes (GATOR TBI)

University of Florida logo

University of Florida

Status

Terminated

Conditions

Traumatic Brain Injury

Treatments

Other: Magnetic Resonance Imaging (MRI)

Study type

Interventional

Funder types

Other

Identifiers

NCT01890304
68-2013

Details and patient eligibility

About

To identify the changes in the brain following repeated sports-related concussion in men's football, women's soccer, and women's lacrosse college athletes by reviewing the findings of MRI studies that look at the structure of the brain and the appearance of the white matter at baseline, during the acute phase of a concussive injury, and upon completion of collegiate athletic play and correlate these findings with standard clinical measures.

Full description

This proposal seeks to study Diffusion Tensor Imaging and functional MRI of the brain at 1) baseline, 2) after concussion and 3) at the end of an athlete's college career. Findings will be compared to standard clinical measures already performed in the management of concussion at the University of Florida Athletic Association and to serum biomarkers already being obtained as part of a UF/ Banyan Biomarker Study. As in the biomarker study, UF athletes on teams with higher incidences of sports related concussion; men's football, women's soccer, and women's lacrosse will be offered enrollment. Longitudinal examinations will allow identification and quantification of concussive DTI findings as comparisons can be made to the individual athlete's baseline data. This will provide valuable correlation of imaging findings with severity of clinical symptoms at the time of injury and also with timing of return to play.

Enrollment

750 patients

Sex

All

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Currently enrolled and active UF student athlete in Mens Football, Womens Soccer, or Womens Lacrosse.
  • Age 18-30

Exclusion criteria

  • Contraindications to MRI, such as retained metal
  • Pregnancy

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

750 participants in 1 patient group

Magnetic Resonance Imaging (MRI)
Other group
Description:
Athletes at risk for mild traumatic brain injury during the course of competitive play or practice. An MRI will be obtained at study entry, following any TBI occuring during sanctioned practice or play, and at study exit.
Treatment:
Other: Magnetic Resonance Imaging (MRI)

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems