Lornoxicam Versus Etodolac After Third Molar Surgery

Kutahya Health Sciences University

Status and phase: Completed; Phase 4

Conditions: Edema; Pain, Acute; Trismus

Treatments: Drug: Lornoxicam 8 Mg Oral Tablet

Study type: Interventional

Funder types: Other

Identifiers

NCT05679453

10

Details and patient eligibility

About

Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction

Full description

20 patients included in study (4 male, 16 female). Lornoxicam and etodolac was given following lower third molar extraction. Pain was evaluated 2., 6., 12., 24., and 48. hours using VAS. Edema was evaluated by measuring tragus-labial commissure, angulus- lateral canthus of eye and angulus mandible-labial commissure. Trismus was evaluated measuring mouth opening by caliper. Edema and Trismus was evaluated by 48. and 168. hours

Enrollment: 20 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Bilateral mesioangular impacted lower third molar
• Asymptomatic Third Molar (No history of infection)
• Systemically Healthy Person
• Person Between aged 18-30

Exclusion criteria

• People who are pregnant and lactation process
• People who had any systemic disease
• People who are gastrointestinal problems
• People who are sensitive to drugs used in study
• Lower Third Molar associated with cysts and infections

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Sequential Assignment

Masking: Double Blind

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20 participants in 2 patient groups

Etodolac

Active Comparator group

Description:

Etodolac, 400 mg tid per a day for four days

Treatment:

Drug: Lornoxicam 8 Mg Oral Tablet

Lornoxicam

Active Comparator group

Description:

Lornoxicam, 8 mg twice per day for four days

Treatment:

Drug: Lornoxicam 8 Mg Oral Tablet