Low Carb vs Normal Carb in Pregnancy

University at Buffalo (UB)

Status: Terminated

Conditions: Gestational Diabetes

Treatments: Other: 100 g carbs; Other: MyPlate

Study type: Interventional

Funder types: Other

Identifiers

NCT03749889

00002745

Details and patient eligibility

About

The overall purpose of this intervention study is to examine whether low-carbohydrate dietary intervention will prevent the development of gestational diabetes mellitus (GDM) in high-risk pregnant women. The results of this study should help further our understanding of how pregnant women can help prevent gestational diabetes mellitus. We hypothesize that a lower carbohydrate diet will prevent the development of GDM.

Enrollment: 11 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 - 40 years old
• BMI > 30 and/or history of gestational diabetes mellitus
• Currently in first trimester of pregnancy with single fetus (e.g. not twins, triplets, etc.)
• Newborns of current participants

Exclusion criteria

• Diabetes (types 1 and 2)
• History of major chronic disease or blood clotting disorders (e.g., cancer, heart disease, kidney disease, hypertension)
• Known fetal anomaly
• History of eating disorders
• Current use of medications that affect appetite or insulin secretion/sensitivity (e.g. stimulants)
• Current use of illegal substances, antipsychotic or opioid substitution medications, alcohol, or tobacco

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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11 participants in 2 patient groups

100 g carbs

Experimental group

Description:

100 grams of carbohydrate allowance for the day

Treatment:

Other: 100 g carbs

MyPlate

Active Comparator group

Description:

Carbohydrate suggestions based on standard MyPlate. 45-65% kcal intake from carbs.

Treatment:

Other: MyPlate