Low Dose Bupivacaine Spinal for Trans Uretral Prostatectomy. (TURP)

Diskapi Yildirim Beyazit Training and Research Hospital

Status and phase: Unknown; Phase 4

Conditions: Benign Prostate Hyperplasia

Treatments: Drug: Heavy Bupivacaine; Drug: Isobaric Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT01861041

PROSTAT

Details and patient eligibility

About

Spinal anesthesia, is used during the transuretheral resection of the prostate.Low dose hyperbaric local anesthetics have been used to enhance the resolution of the spinal block. We compared the efficacy and duration of the spinal block with two different bupivacaine baricities.

• Group I: low dose isobaric group
• GroupII: Low dose hyperbaric group

Full description

Patients undergoing TURP were randomly allocated into two groups.

• Group I: Received fentanyl 20 µgr (0.4ml),heavy bupivacaine 0.5% (1.5 ml)and normal saline % 0.9 NaCl ( 1.1ml)
• Group II: Received fentanyl 20 µgr (0.4 ml), plain bupivacaine 0.5%(1.5 ml) normal saline 0.9% NaCl (1.1 mL) in total bupivacaine 0.25% (3ml) intrathecally.

Onset and duration of the sensory block, the degree of the motor block, side - effects and perioperative analgesic requirement assesed.

Enrollment: 52 estimated patients

Sex: Male

Ages: 50 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 50-85 years ASA 1-4 BENİGN PROSTAT HYPERPLASİ

Exclusion criteria

• Allergy of study drugs
• Morbid obesity
• Spinal anesthesia contrindications
• Bleeding dyscrasias

Trial design

52 participants in 2 patient groups

Heavy Bupivacain, Local anesthetic, Amp

Experimental group

Description:

Heavy bupivacaine 7.5 mg (1.5 ml), 20 microgram fentanyl(0.4 ml), 1.1 ml saline , Total 3 ml

Treatment:

Drug: Heavy Bupivacaine

Isobaric spinal, Local anesthetic, Amp

Active Comparator group

Description:

7,5 mg isobaric bupivacaine, 20 microgram (0.4 ml)fentanyl, 1.1 ml saline, Total 3 ml

Treatment:

Drug: Isobaric Bupivacaine