Low Dose of Diltiazem for Rate Control of Atrial Fibrillation

Seoul National University

Status and phase: Unknown; Phase 4

Conditions: Atrial Fibrillation

Treatments: Drug: low dose diltiazem

Study type: Interventional

Funder types: Other

Identifiers

NCT00834925

Diltiazem Af

Details and patient eligibility

About

This study is to show the efficacy and safety of low dose diltiazem for the treatment of atrial fibrillation with rapid ventricular response in emergency room. We will compare the standard dose of diltiazem(0.25mg/kg) with low dose diltiazem(0.1mg/kg)in atrial fibrillation with rapid ventricular response in ED.

Enrollment: 380 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• atrial fibrillation with rapid ventricular response in emergency room

Exclusion criteria

• age<18
• systolic blood pressure<90mmHg
• no consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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380 participants in 2 patient groups

standard dose diltiazem

No Intervention group

low dose diltiazem

Experimental group

Treatment:

Drug: low dose diltiazem