Low Dose of Midazolam is Superior to Conventional Dose for Rapid Sequence Intubation in Emergency Department (ED)

Seoul National University

Status: Completed

Conditions: Intubation

Treatments: Drug: Low dose midazolam

Study type: Interventional

Funder types: Other

Identifiers

NCT00783731

RSI study

Details and patient eligibility

About

Midazolam has been used in rapid sequence intubation for a long time, and the recommended dose is 0.1mg/kg. In some studies, however, the reduced dose has been used with the concern of hemodynamic instability. We would like to investigate that the low dose midazolam could be used rather than the standard recommended dose, and also compare it to the etomidate, recently used sedatives, with respect to the side effects and the easy performance of intubation.

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who need rapid sequence intubation in emergency room

Exclusion criteria

• in hypotension(systolic blood pressure less than 90 mmHg
• severe trauma patients
• pregnant
• allergic to midazolam, etomidate

Trial design

0 participants in 1 patient group

Low dose midazolam

Experimental group

Treatment:

Drug: Low dose midazolam