Low-dose Radiotherapy in iNHL

Chinese Academy of Medical Sciences & Peking Union Medical College

Status and phase: Enrolling; Phase 2

Conditions: Low-dose Radiotherapy; Indolent Lymphoma

Treatments: Radiation: Low-dose radiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05543070

CLCG-iNHL-01

Details and patient eligibility

About

The current study is a phase II multi-center single arm trial to evaluate the efficacy and safety of low-dose radiotherapy (3 Gy*4f) in indolent lymphoma.

Enrollment: 73 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pathology proved iNHL
• ECOG PS ≤3
• Signed Informed consent

Exclusion criteria

• History of radiotherapy at the same site
• Primary malignant lymphoma of the gastrointestinal tract
• CTV (Clinical Target Volume)>500ml
• Others that researchers consider inappropriate

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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73 participants in 1 patient group

Low-dose Radiotherapy

Experimental group

Description:

Involved-site radiotherapy (3 Gy\*4f) in one week

Treatment:

Radiation: Low-dose radiotherapy