Low Dose Statins, Ezetimibe and Nutraceuticals (TACO)

University of Roma La Sapienza

Status and phase: Unknown; Phase 4

Conditions: Coronary Artery Disease

Treatments: Drug: statin + ezetimibe; Drug: statin + ezetimibe + Nutraceuticals

Study type: Interventional

Funder types: Other

Identifiers

NCT03277079

123/D/2017

Details and patient eligibility

About

It remains unknown if the association between moderate to low intensity statin therapy and ezetimibe and nutraceuticals might have a therapeutic role in high-intensity statin intolerant patients

Full description

The aim of this study will be to evaluate whether the association between statin and exetimibe vs statin + ezetimibe + nutraceuticals can lead to higher percentage of LDL target achievement

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients with angiographically assessed diagnosis of coronary artery disease

Exclusion criteria

None

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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100 participants in 2 patient groups

statin + ezetimibe

Active Comparator group

Description:

Low dose statin associated with ezetimibe

Treatment:

Drug: statin + ezetimibe + Nutraceuticals

Drug: statin + ezetimibe

statin + ezetimibe + Nutraceuticals

Active Comparator group

Description:

Low dose statin associated with ezetimibe and Nutraceuticals

Treatment:

Drug: statin + ezetimibe + Nutraceuticals

Drug: statin + ezetimibe