Low-intensity Exercise in Metabolic Syndrome

Wroclaw University of Health and Sport Sciences

Status: Completed

Conditions: Hypertension; Hyperlipidemias; Glucose Metabolism Disorders; Obesity; Metabolic Syndrome

Treatments: Behavioral: Low-intensity, general-fitness exercises; Behavioral: Psychoeducation

Study type: Interventional

Funder types: Other

Identifiers

NCT04346836

59/0203/S/04

Details and patient eligibility

About

People with metabolic syndrome (MetS) are characterized by a lower quality of life in terms of reduced vital activity, emotional state, and social functioning. Therefore, the investigator's aim was to determine the impact of low-intensity exercise and psychoeducation on depression symptoms and self-perceived stress in women with MetS.

Full description

Metabolic syndrome (MetS) is currently one of the major threats to health in highly developed societies. A recent study has demonstrated that depression may be significantly associated with MetS in people aged 60 years or over. The more components of MetS that are evident in the individual, the more depressive symptoms this individual is likely to exhibit.

MetS treatment is essentially founded on implementing lifestyle changes which involve regular physical activity and healthy dietary habits. Systematically undertaking exercise has a beneficial influence on health, particularly on cardiovascular system functions as well as the quality of life and depression status in middle-aged and older women with MetS.

Previous work has shown moderate or high intensity exercise to be optimal for the treatment of MetS. Nevertheless, many patients with MetS have hypertension and obesity. Therefore, for safety reasons, the patient's condition during intensive group exercises should be constantly monitored by a physician or specialized equipment, which generates costs and may limit the availability of this type of intervention.

Hence, the investigator's aim was to determine the impact of 12 weeks of low-intensity exercise, combined with psychoeducation, on the severity of depression symptoms and self-perceived stress in women with MetS.

Enrollment: 88 patients

Sex: Female

Ages: 60 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

The presence of Metabolic Syndrome diagnosed using the International Diabetes Federation-recommended criteria (2006):

• "mandatory" central obesity (defined as waist circumference ≥ 80 cm in females),

and any two of the following:

• raised triglycerides (>150 mg/dL),
• reduced HDL cholesterol (50 mg/dL in females),
• elevated blood pressure (BP; systolic BP > 130 or diastolic BP > 85 mm Hg) ,
• increased fasting plasma glucose (>100 mg/dL),

Exclusion criteria

• disturbed cognitive functions (Mini-Mental State Examination > 23),
• the inability to move independently or a motor disability precluding exercise,
• serious neurological or orthopaedic conditions (e.g., advanced Parkinson's disease, severe stroke consequences),
• attending fewer than 13 intervention sessions.

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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88 participants in 2 patient groups

Metabolic Syndrome

Experimental group

Description:

Elderly women with Metabolic Syndrome 24 sessions of low-intensity exercise and psychoeducation, twice a week over 12 weeks.

Treatment:

Behavioral: Psychoeducation

Behavioral: Low-intensity, general-fitness exercises

Non-Metabolic Syndrome

Experimental group

Description:

Elderly women without Metabolic Syndrome. 24 sessions of low-intensity exercise and psychoeducation, twice a week over 12 weeks.

Treatment:

Behavioral: Psychoeducation

Behavioral: Low-intensity, general-fitness exercises