Low Intensity Pulsed Ultrasound Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis

Ministry of Health and Sports, Myanmar

Status: Unknown

Conditions: Osteoarthritis; Musculoskeletal Diseases; Rheumatic Diseases; Osteoarthritis, Knee

Treatments: Device: High intensity continuous ultrasound; Device: Low intensity pulsed ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT04406337

PMR

Details and patient eligibility

About

To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis

Full description

Knee osteoarthritis is a common disorder affecting elderly and obese. Currently, there are 3 types of treatment; pharmacological, non-pharmacological and surgery. Though ultrasound, a non-pharmacological treatment, is increasingly used in knee osteoarthritis, the advantages and disadvantages of low intensity pulsed ultrasound (LIPUS) and high intensity continuous ultrasound (HICUS) are yet to be clarified. Therefore, a randomized control trial will be done to compare LIPUS and HICUS in participants with knee osteoarthritis presenting to Department of Physical Medicine and Rehabilitation, Yangon General Hospital, Myanmar.

Enrollment: 86 estimated patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants with knee pain (VAS 3 to 6)
• Kellgren and Lawrence grade 2 and 3 in X' ray knee joint

Exclusion criteria

• Rheumatoid arthritis, Gouty arthritis, Spondyloarthropathies, Metabolic arthropathies
• Infection of knee joint
• Tumor of knee joint
• History of hypersensitivity to heat
• Previous knee surgery in affected side
• Intra-articular injection within previous 3 months
• Participants taking treatment with other physical modalities such as low-level laser therapy and Trans Cutaneous Electrical Nerve Stimulation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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86 participants in 2 patient groups

Low intensity pulsed ultrasound

Experimental group

Description:

Participants in this arm will receive low intensity pulsed ultrasound therapy on the affected knees for 20 minutes per day, 5 days a week for 4 weeks. Conventional physiotherapy of quadriceps muscle exercise and health education about life style will also be given.

Treatment:

Device: Low intensity pulsed ultrasound

High intensity continuous ultrasound

Active Comparator group

Description:

Participants in this arm will receive high intensity continuous ultrasound therapy on the affected knees for 10 minutes per day, 5 days a week for 4 weeks. Conventional physiotherapy of quadriceps muscle exercise and health education about life style will also be given.

Treatment:

Device: High intensity continuous ultrasound